RawGanirelix powderis an injectable competitive gonadotropin-releasing hormone antagonist (a decapeptide GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Raw Ganirelix powder is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation. Raw Ganirelix powder is marketed by Merck & Co., Inc. as Orgalutran.

Raw Ganirelix powder is rapidly absorbed following subcutaneous injection with maximum serum concentrations reached approximately one hour after dosing.
Product Name Raw Ganirelix powder
Chemical Name Ac-DNal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla -NH2;Raw Ganirelix powderum
Brand Name Orgalutran, Antagon
Drug Class Peptide
CAS Number 124904-93-4 (123246-29-7)
InChIKey GJNXBNATEDXMAK-PFLSVRRQSA-N
Molecular Formula C80H113ClN18O13
Molecular Weight 1570.347 g/mol
Monoisotopic Mass 1568.842 g/mol
Melting Point N/A
Biological Half-Life 16.2 hours
Color White
Solubility 0.25mg/ml~30mg/ml in DMSO and DMF
Storage Temperature −20°C
Application a Gonadotropin Releasing Hormone Antagonist, used in assisted reproduction to control ovulation.

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